A CLINICAL STUDY FOR
ADULTS WITH LIVER CIRRHOSIS

Hepatic encephalopathy (HE) is a complication of liver cirrhosis (liver damage). It affects nearly half of people with cirrhosis.1. Because of the damage, the liver

doesn’t work as well as it should, and some toxins stay in the body. HE occurs when too many toxins build up in the bloodstream and reach the brain.

It can cause symptoms like:

confusion

personality changes

lack of energy

inappropriate behavior

sleep problems

loss of small hand movements and tremors in hands and arms.

Adults who have been diagnosed with liver cirrhosis but who don’t yet have HE may be eligible to join.

Who can participate?

Participants may be eligible for the study if they:

Are between the ages of 18 and 85

Have a diagnosis of liver cirrhosis

Have not been diagnosed with overt HE (a severe form of HE)

Do not experience any cognitive issues due to HE or any other illness

Do not have an active COVID-19 infection

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